What is Brufen 400mg?
Brufen 400 mg Tablets (Ibuprofen), commonly known as Ibuprofen, is a medication that helps treat body pains, fever, sprains, strains, arthritis, pain after surgical operations, and in higher doses, it helps reduce inflammation.
It belongs to a category of drugs known as a nonsteroidal anti-inflammatory drug(NSAID), So nonsteroidal anti-inflammatory drugs help with pain relief, fever, blood clots, and also help in reducing inflammation.
 
This helps in relieving pains like menstrual cramps, migraines, and even rheumatoid arthritis. It is available in the form of tablets, gel, spray, or mousses, but Brufen 200mg is an over-the-counter medication that is buy without any prescription.
 
Uses of Brufen 400mg
Brufen 400 mg Tablets is using as a medication for different types of illness and symptoms; List below:
Different types of arthritis like osteoarthritis, rheumatoid arthritis, and rheumatoid arthritis
Inflammation and pain caused due to broken or dislocated bones
Relieving problems caused due to menstruation
Bone and muscle injuries like strains, back pains, sprains, tendonitis, and rheumatism
Dental pains
Reducing high fever
Problems caused post-surgery
For minor pains like headaches, the use of medicine is short-term, but in the case of anti-inflammatory-related issues like arthritis, the service may be long-term.
Although medicine is using to treat inflammation and pain symptoms, it does not cure the underlying condition. Brufen 400mg is added to some medications, for example, to create a remedy for cold and flu.
 
Side Effects of Brufen 400mg
Like any other medication, Brufen 400mg can cause also cause some side effects; some are common; some may be rare and are very rare. Common side effects may include:
Nausea
Heartburn
Vomiting
Diarrhea
Stomach or intestinal pains
Constipation
Skin Rashes
Buzzing or ringing in the ears
Yellow-colored skin or eyes
Reduced urine
Running nose
 
Common Side effects 
Stomach inflammation
Hypertension(high blood pressure)
Dizziness
Bloating
Ulcers in the digestive system
Fluid retention or edema
Worsening asthma symptoms
If you experience dizziness after taking Brufen 400 mg Tablets, do not drive or operate any heavy machinery. Even though most of the symptoms are list above, a person might experience stomach bleeding in sporadic cases. The signs include passing black stools or vomiting blood. In the long term, Brufen remembers to reduce fertility in women, but the problem reverses after the treatment is over.
 
Brufen 400 mg Tablets Drug Interactions:
Some medications can interfere with the effects of other medicines and may cause a drug reaction. Therefore, Brufen 400mg is known as drug interaction in medical terms.
There an about 468 drugs that are known to interact with Brufen 400mg. Some of them may include:
 
Anti-inflammatory painkillers:
 
Brufen 400mg is taking with anti-inflammatory painkillers like Voltaren, naproxen, or indomethacin as they are all painkillers. It also enhances the risk of stomach bleeding.
 
Antihypertensive medications:
Antihypertensive medications are drugs taking to treat hypertension, so Taking Brufen 400mg with these may increase blood pressure.
Digoxin:
Digoxin is a drug used to treat atrial fibrillation. But with Brufen 400mg, can result in high blood pressure.
Aspirin:
Aspirin, when taken along with Ibuprofen, increases the risk of stomach bleeding. Low doses of aspirin help with blood thinning. Brufen 400mg, taken along with a low dosage of Aspirin, diminishes the blood-thinning effect.
Methotrexate:
Methotrexate is using to treat some autoimmune diseases and cancer. Brufen 400mg Tablet makes it hard to eliminate methotrexate from the body. Brufen 400mg may lead to dangerous levels of methotrexate levels in the body.
Lithium:
Lithium is using to treat some mental disorders. When taken with Brufen 400mg, it becomes hard for the body to excrete Lithium out of body, which can be dangerous.
Tacrolimus:
Tacrolimus is using after an organ transplant. This drug’s job is to make sure that the immune system does not reject the organ transplant. Tacrolimus and Brufen 400mg, when taken together, can cause kidney damage.
Selective serotonin reuptake inhibitors (SSRIs):
Drugs like fluoxetine, citalopram, paroxetine, and sertraline, when taken with Brufen 400mg, increase bleeding risk.
Warfarin:
Warfarin is an anticoagulant drug. Anticoagulants are drugs that stop blood from clotting, so blood thinners. Brufen 400mg can prevent anticoagulants from working. Before taking Brufen 400 mg Tablets, one must consult an experienced pharmacist or a doctor.
 
How long should Brufen 400mg be continued?
If Brufen 400mg is taking daily, it is continuing for more than 30 days.
Brufen 400mg is a harmless effective pain killer for the most part, but it might start causing some side effects when taken daily. So, it’s advisable not to continue Brufen 400mg after 30 days.
The dosage can range from 400 mg to 800 mg a day and can be taken four times a day for 30 days. Post that the medicine is taking unless consulted otherwise by your doctor.
How Brufen 400mg works?
Brufen works by blocking the effect of some natural chemicals called cyclooxygenase (COX) enzymes. Cyclooxygenase (COX) enzymes are responsible for making other chemicals in the body called prostaglandins(PG). Prostaglandins(PG) is a chemical that the body release when hit by some illness or injury, so are responsible for causing inflammation and pains. These compounds are released in the brain and even cause fever. By blocking prostaglandins, the body doesn’t feel any problem caused by illness or injury.
How to take Brufen 400mg?
This drug is taking mouth.so taking every 4 to 6 hours with a glass of water. If you get an upset stomach after taking it with water, try taking it with food, milk, or an antacid.