Brand name: Viropil
Composition: Dolutegravir, Lamivudine and Tenofovir Disoproxil Fumarate
Maketed by : Emcure
Dosage form: Tablets
Dose: 50mg+300mg+300mg
Each bottle contain of 30 tablets.
 
Viropil  belongs to antiviral drugs which will inhibits the human immunodeficiency virus from replicating in your body.
Viropil is a combination medicine of dolutegravir/lamivudine/Tenofovir Disoproxil which are used to treat against the HIV and the virus that can cause acquired immunodeficiency syndrome (AIDS).
Viropil is not a curable for HIV or AIDS.
Viropil is a prescription drug which is used under proper guidance of doctor.
 
INDICATIONS OF VIROPIL
Viropil is indicated in concomitant use with other antiretroviral drugs to treat the disease like HIV-1 (human immunodeficiency virus) in adult and pediatric patients weighing at least 30-35kg.
Viropil will helps to reduce the amount of HIV in the body and immune can work better.
Viropil will not give chance of getting HIV complications like cancer or new infections and progress the quality of life.
 
HOW TO USE AND ADMINISTER THE DRUG
Before starting or during treatment with Viropil , take the test for the patients for hepatitis B virus Infection.
The usual dose of viropil is three drug fixed-dose combination product containing 50mg of dolutegravir, 300mg of lamivudine, and 300mg of Tenofovir DF used for HIV-1 infected adult and pediatric patients weighing at least 30-35kg.
One tablet once daily given orally.
The drug viropil may have with or without food but probably taken with food to enhance exposure
 
OVERDOSAGE
There is no specific treatment for overdose, If someone cause overdose then patients supposed to provide standard supportive treatment and monitored for evidence of toxicity. Incase of dolutegravir overdose, the symptoms like breathing trouble will occur.
In case of lamivudine and Tenofovir provide continues hemodialysis for 4 hours removed approx 10% of drug.
 
SIDE EFFECTS CAUSED BY VIROPIL
Lactic Acidosis/severe hepatomegaly with steatosis
Exacerbation of hepatitis B
New onset or worsening renal impairment
In  patients Co-infected with HIV-1 and hepatitis C will have Hepatic decompensation
Pancreatitis
Reduces in bone Mineral density
Immune reconstitution syndrome
Fat redistribution